Obagi Tretinoin 0.05% Gel

Acne treatment gel
Retinoid indicated for the topical treatment of acne vulgaris. Available by prescription only, all Obagi tretinoin formulations are non-comedogenic and fragrance free.

Prescription required. Contact your healthcare provider to purchase, or find a nearby physician who offers this product.
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Tretinoin is the generic name for synthetic, first-generation all-trans-retinoic acid. Topical tretinoin first arrived on the dermatology scene in the 1960s. It is a prescription drug approved to treat acne, and in a few other FDA-approved products, to treat fine facial wrinkling, limited psoriasis, and other conditions.

Tretinoin Gel is a translucent to opaque, pale yellow gel containing 0.05% tretinoin, by weight.
Each gram contains:
Tretinoin Gel is a translucent to opaque, pale yellow gel containing 0.05% tretinoin, by weight. Other components of this formulation are benzyl alcohol, butylparaben, butylated hydroxytoluene, carbomer homopolymer Type C, ethylparaben, fish collagen hydrolyzates, glycerin, isobutylparaben, methylparaben, octoxynol 9, phenoxyethanol, propylparaben, purified water, sodium hyaluronate, and trolamine

Jennifer Britt

28 days ago

Being dilligent with this product has been one of the best decisions I have ever made. My skin looks great and I attribute most of that to tretinoin!

Joanna Edmunds

29 days ago

I have been ising this for a while now and i can see a big difference in my pore size and firmness of my skin.

Melanie Hallback

1 months ago

Love this. Great for clearing breakouts

Tracy Patterson

1 months ago

For 2 years I used prescription Tretinoin and had horrible irritation, I don't get that with this product, it's extremely effective however my skin tolerates this so much better, especially combined with the Obage Rebalance.

Rebecca Abshire

1 months ago

The number one thing you can add yo your skincare rputine to see dramatic improvement in all areas

Angella Rogers

2 months ago

I've been using this gel each night with the Nu-Derm set and seeing boosted results 2 weeks in. Love that this is a gel with easy application.

Jessica Alvarado

3 months ago

Excited to comtinue erasing the fine lines

Eliana Vargas

3 months ago

Great stuff . Big diffeence i see in my skin

Carolyn Merica

4 months ago

Great first step in lightening my sun damaged skin.

Crystal Corren

4 months ago

Madison Nguyen

4 months ago

After using it for 2 months, I've notice my skin texture is much better.

Brittany Black

4 months ago

Love it

Andrea Atzinger

5 months ago

Great stuff. Gentle, yet effective. I've been using for years now!

Katie Wicker

5 months ago

I love this product. The gel dries quickly and isn't tacky.

Erika Patterson

5 months ago

My first time ever using tretnoin. I was worried my highly sensitive skin would veto the product, but other than the expected dryness in the first few weeks of use, I experienced NO negative affects. I just purchased a second tube and moved up to the .10% cream. So far, so good!

Taylor Surratt

7 months ago

Must have

Sarah Stephenson

7 months ago

Ive used both the cream and gel formulas and i prefer the gel. It feels better on my face and i love how freah my skin looks!!

Stephanie Springer

7 months ago

Amazing

Heather Solar

7 months ago

Does wonders for my complexion

Ashley Williamson

8 months ago

Good product

Alixzandrah Miller

11 months ago

Same consistency as other retinols. I didnt purge with this or have any issues.

Laura Napier

1 years ago

I have previosuly been usong the cream and it was great. But this gel applies on much smoother and able to spread more! This is a must have! My skin heals so fast from breakouts now and it makes me skin smooth I use this every night :)

Paige Usry

1 years ago

Game changer in texture and fine lines

Marti Flippo

1 years ago

love this product!

Patsy Grooms

1 years ago

Great product

Ashlyn Jordan

1 years ago

The best retinol ive used

Lori Hagen

1 years ago

Its a basic need for my skincare

Paula Jackson

1 years ago

This Tretinoin gel is my favorite consitancy! The gel glides easily and imo is easier to work into the skin then the other traditional consistancies. The changes in my skin are dramatic and pushed through the dry phase!

Jordana Sarver

1 years ago

At first my skin did not like it but after a few weeks my skin barrier adjusted and i love it! Fine lines goodbye! And hello clear skin!

Nicole Giranis

1 years ago

Love how smooth the tret gel goes on! Will forever use this over the tret cream

Libby Bates

1 years ago

Helps my skin

Carol Green

1 years ago

This product does not cause my rosacea to flare up like other retinol products. Goes on smoothly and is a wonderful daily part of my face and neck routine. Just wish there was more in a tube.

Sabrina L Rogers

1 years ago

i have acne and wrinkles. use of this product sodtens my skin

Jessica Wingard

1 years ago

I peeled for several weeks, but the results were worth it!

Allison Rosenwasser

1 years ago

I have been using this product for a little while now and i have definitely seen a difference in my skin. Already got it again.

Lyndsy Hester

2 years ago

If you only do one thing after washing your face, this and sunscreen are gold for your skin

Marisa Redden

2 years ago

powerful and effective

Kassandra Gutierrez

2 years ago

This was a lifesaver when I started breaking out, highly recommend.

Julia Callahan

2 years ago

Easy tp apply with great results.

Nicolette Gietzen

2 years ago

Excellent product

Ronda Hill

2 years ago

😃

Tamara Smith

2 years ago

I cant rave about this magic tube enough! It has been like an eraser for my face! I'm so thankful for this entire product line. It's transforming my skin day by day to a more youthful and vibrant look. Obagi rocks!

Emily Bryant

2 years ago

Love this product! Gentle enough for my sensitive skin!

Stacey Cribbs

2 years ago

Love this prodcit!

Sara Krupinsky

2 years ago

Liquid gold!

Danielle Capogna

2 years ago

Helps with trouble areas

Jennifer Cockrell

2 years ago

Love thus product!!

Sara Adams

2 years ago

Great product

Lindsay Sanders

2 years ago

Favorite

Darcie Lee

2 years ago

Wonderful gel, goes on smoothly and really helps with tone

Sally Taylor

3 years ago

I lke to mix the gel tretinoin with the blender for me it blends easier than the cream But i love them all

Sarah Purcell

3 years ago

Has done wonders for my skin!!

Laura Brien

3 years ago

The only tretinoin that doesnt irritate my skin. It doesnt smell bad and absorbs right in.

Ashley Moore

3 years ago

This has really helped my skin peel away the bad and making my skin turn over the cells for a vibrant new look.

Michelle Kavadas

3 years ago

I love this product. Makes my skin feel smooth

Mariah Vasquez

3 years ago

my favorite tret ever!!!!

Tina Smith

3 years ago

Wotks great

Blanche Provence

3 years ago

Amazing. Works so well without irritating my skin.

Nikki Hebert

3 years ago

I use this nightly! A staple in my skin care regimen! Retin A is a must for fighting aging.

Lily Lusty

3 years ago

Love the Obagi Written a .05% gel. It does not leave your face feeling greasy but still hydrated.

Rima chehab

3 years ago

I love this. I am getting such great results

Jaclyn Zatezalo

3 years ago

Love the gel!! The cream doesn’t feel as good and every morning I wake up with glowing skin!! I’ve noticed a more even skin tone, smaller pores, and overall brighter skin!

Laura Whiton

3 years ago

Great

Charissa Ondovic

4 years ago

I absolutely love this product. Helps with acne and fine lines. Leaves my skin smooth

Megan Culbreth

4 years ago

Hand down my favorite skincare product I’ve ever owned! This is a must have product!

Janice Williams

4 years ago

Only product that ever used that faded my dark spots.

ALex Curiel

4 years ago

love it

Need to Know

IMPORTANT SAFETY INFORMATION

Tretinoin Gel Indication: Tretinoin Gel is indicated for topical application in the treatment of acne vulgaris.

Important Safety Information: For Topical Use Only

Contraindications: Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

Please click here for full Prescribing Information

IMPORTANT SAFETY INFORMATION

Tretinoin Gel Indication: Tretinoin Gel is indicated for topical application in the treatment of acne vulgaris.

Important Safety Information: For Topical Use Only

Contraindications: Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

Please click here for full Prescribing Information

Precautions: Exposure to sunlight, including sunlamps, should be minimized during the use of Tretinoin Cream and Gel, and patients with sunburn should be advised not to use the product until fully recovered.

Patients who have considerable sun exposure due to occupation and those with inherent sensitivity to the sun should exercise particular caution. Use of sunscreen products and protective clothing over treated areas is recommended when exposure cannot be avoided.

Weather extremes, such as wind or cold, also may be irritating to patients using tretinoin.

Tretinoin Gel should be kept away from the eyes, the mouth, angles of the nose, and mucous membranes. Topical use may induce severe local erythema and peeling at the site of application. If the degree of local irritation warrants, patients should be directed to use the medication less frequently, discontinue use temporarily, or discontinue use altogether.

Tretinoin has been reported to cause severe irritation on eczematous skin and should be used with utmost caution in patients with this condition.

Pregnancy Tretinoin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Adverse Reactions The skin of certain sensitive individuals may become excessively red, edematous, blistered, or crusted. If these effects occur, treatment should be discontinued or adjusted to a level the patient can tolerate.

To report SUSPECTED ADVERSE REACTIONS contact FDA at fda.gov/medwatch or call 1-800-FDA-1088.

IMPORTANT SAFETY INFORMATION

Tretinoin Gel Indication: Tretinoin Gel is indicated for topical application in the treatment of acne vulgaris.

Important Safety Information: For Topical Use Only

Contraindications: Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

Please click here for full Prescribing Information

How to Use

Morning Routine:

  • Apply a moisturizer, preferably with sunscreen, that will not aggravate your acne.

Nighttime Routine:

  • Wash with a mild soap and dry skin gently
  • Wait 20 to 30 minutes to allow skin to completely dry
  • Squeeze no more than half an inch of medication onto fingertip; more medication will not yield faster or better results and may cause irritation
  • Apply onto face, covering affected area lightly, starting with your forehead, chin, and both cheeks, then spread over the entire affected area
  • Avoid corners of the nose, mouth, eyes, and open wounds
  • Tretinoin is for topical use, only
  • Tretinoin should be applied once daily, or as directed by physician
  • Use Obagi Tretinoin Gel with caution if allergic to fish
  • Please ensure to always read and follow the Patient Instruction in the Prescribing Information leaflet that accompanies your tretinoin prescription
  • Tretinoin acne treatment should be kept away from the eyes, the mouth, paranasal creases, and mucous membranes
  • Application of excessive amounts of gel will not provide incremental efficacy
  • Store tretinoin gel 0.05% at controlled room temperature 20° - 25°C (68° - 77°F) with excursions permitted between 15°-30°C (59° - 86°F)
  • Protect from freezing

Morning Routine:

  • Apply a moisturizer, preferably with sunscreen, that will not aggravate your acne.

Nighttime Routine:

  • Wash with a mild soap and dry skin gently
  • Wait 20 to 30 minutes to allow skin to completely dry
  • Squeeze no more than half an inch of medication onto fingertip; more medication will not yield faster or better results and may cause irritation
  • Apply onto face, covering affected area lightly, starting with your forehead, chin, and both cheeks, then spread over the entire affected area
  • Avoid corners of the nose, mouth, eyes, and open wounds
  • Tretinoin is for topical use, only
  • Tretinoin should be applied once daily, or as directed by physician
  • Use Obagi Tretinoin Gel with caution if allergic to fish
  • Please ensure to always read and follow the Patient Instruction in the Prescribing Information leaflet that accompanies your tretinoin prescription
  • Tretinoin acne treatment should be kept away from the eyes, the mouth, paranasal creases, and mucous membranes
  • Application of excessive amounts of gel will not provide incremental efficacy
  • Store tretinoin gel 0.05% at controlled room temperature 20° - 25°C (68° - 77°F) with excursions permitted between 15°-30°C (59° - 86°F)
  • Protect from freezing

FAQs