Obagi Tretinoin 0.1% Cream

Acne treatment cream
Topical treatment for acne vulgaris. Available by prescription only, all Obagi tretinoin formulations are non-comedogenic and fragrance free.

Prescription required. Contact your healthcare provider to purchase, or find a nearby physician who offers this product.
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Tretinoin is the generic name for synthetic, first-generation all-trans-retinoic acid. Topical tretinoin first arrived on the dermatology scene in the 1960s. It is a prescription drug approved to treat acne, and in a few other FDA-approved products, to treat fine facial wrinkling, limited psoriasis, and other conditions.

Available in multiple strengths and formulations by prescription only, Obagi tretinoin creams and gel work deep inside the skin to treat acne.
Each gram contains:
Tretinoin 0.1%, stearic acid, isopropyl myristate, polyoxyl 40 stearate, stearyl alcohol, xanthan gum, sorbic acid, butylated hydroxytoluene, and purified water

JANET VANMETER

6 days ago

Excellent product!

Courtney Strong

10 days ago

I haven't had any sensitivity or dryness, only results

Allison Creveling

15 days ago

This is the product if youre ready to realky fight aging!

Taylor Surratt

1 months ago

Reallt helping with my friends back acne

Julie Dockendorf

3 months ago

This really works. Super smooth product that helps decrease dine lines and wrinkles. Build up to tolerate, but great produxt

Brionna Thomas

4 months ago

Never received

Katie Farris

4 months ago

My holy grail product! A must in every skincare routine!

Karen Easter

5 months ago

This makes my skin peel and looks better after

Cameo Smith

5 months ago

Very potent cream - i use it twice a week abd it leaves ny skin fresh and bouncy!

Ashley Skowron

6 months ago

This is worth every penny. Smooths my skin so its baby soft and i have no visable pores. I am turning 40 this year ans have had hormal acne all my life this product cleared my skin and helped reduce scarinf and even my texture. Thank you obagi

Lunette Vargas

6 months ago

Works great

Karla Lainez

8 months ago

Amazing

Amandeep Kaur

8 months ago

I have textured, oily and acne prone skin. Have been using tret for a few months now and noticing improvements in my skin.

Jamie Deaton

8 months ago

Great, trusted brand of tretinoin. Ive used it nightly for 6 years and frequently get comments on my skin.

Karla Mancilla

8 months ago

Obagi's tretinoin is second to none!!! If you want the best then it has to be Obagi!!! Its just much better than even the brand name Retin-A!!!

Queen Overstreet

8 months ago

Love this

Veronica Smith

9 months ago

Love this product

Laura Napier

9 months ago

This tretinoin cream has changed my skin so much! My face is smoother. If I have a breakout it goes away so quick, it is almost gone after a day!

Brittnay Velasquez

9 months ago

Vitamin a

Kelly Betts

10 months ago

Been using for years, it teally helps my skin look fresh!

Julie Kalahar

11 months ago

This is the best product for the skin surface. Minimizes fine lines and wrinkles. Love this product.

Monica Joosten

1 years ago

love when I see the results of this little tube!!

Courtney Pearson

1 years ago

I am so happy worh how well this product works. It has helped with making ny Botox treatments last a little longer. A must have!

Patsy Grooms

1 years ago

Great profuct!

Amber Latif

1 years ago

I started this with my wedding 2 months out. Im one month out now and am so happy to say I am putting a pause on using this because my hyperpigmentation has nearly disappeared in just 4 weeks! I peeled so much - it was so satisfying waking up with such dramatic results

Lori Foglia

1 years ago

This is a must have for your skin care routine.

Paula Black

1 years ago

Perfect for those winter months!

MaryLou CIARLO

1 years ago

You'll definitely see a difference. I have mature skin. After using the product for three weeks, my skin has a rosy glow and is smooth and even.

Cait Massie

1 years ago

great!

Amber Gentille

1 years ago

Love this product. Face is clearer and sun spots gone

Naomi Melendez

1 years ago

Best Retinol cream

Marisa Redden

1 years ago

strong but mighty! helpful that is

Rima chehab

1 years ago

obagi has the best skin care line. Everything about this product is great.

Yolanda Riley

1 years ago

This is AMAZING!! My skin is always on point after a week of using. Love it!!

Julie Higginbotham

1 years ago

Great for wrinkles and acne

Yiu Womg.

1 years ago

good

Stephanie Chaffin

1 years ago

Great product

Kelie Alaniz

1 years ago

Cant live without this

Tina Tinoco

1 years ago

I believe this product is why i get so many compliments on my skin. Im 49 but look 40. Honestly.

Alexandra Jensen

2 years ago

Important addition to the line!

Sohaila Mahini

2 years ago

I use this one in combination with o.o5 every other night and love it. No irritation and a little bit goeas a long way.

Gabriella Mossini

2 years ago

A drop every night (or every other night) keeps the wrinkles and lines away. I use the tretinoin cream mostly on my forehead and around my mouth lines and i have see such a change. I dont use my cream every night, but every other or 3 times a week i will include it in my pm routine

Adriane Ayerdis

2 years ago

Love this percentage!

Angela Ables

2 years ago

Works great and you only need to use a little

Monica Correll

2 years ago

I have noticed that my skin looks better and my pores are much smaller.

Luisa Salazar

2 years ago

Works wonderful to smooth out any finelines and. Ery happy with the results.

Karen Smilie

2 years ago

Love this stuff. Mix with blender or skin lightening cream at night. But only every 3rd night. I peel if i use this too often

Candida Manion

2 years ago

It has helped my skin tone and complexion a lor, besides the fine lines. This is enough for night

Jessica Peine

2 years ago

I recently switched to this from .05% and I love the results so far. My skin has adjusted very quickly and I plan to use this for the long run. My acne is reduced even more. I have a nice glow! Highly recommended!

Danielle Edwards

2 years ago

Miracle product. Helps with everything from acne, redness, to scarring and pores size.

Sarah Scott

2 years ago

My skin has never been smoother!

Nerissa Murray

2 years ago

Great results and gentle on my skin

Kristen Jurado

3 years ago

Strong product, regular use produces soft more more yourhful skin!

Lindsey Gierlinski

3 years ago

Love it

ASSOUMAHU DIALLO

3 years ago

Good

Michelle McManus

3 years ago

Secret weapon to erasing brown patches

Brandie Dye

3 years ago

I swear by this product!! Ive been using this for 12yrs and cant live without!!

Jennifer Pipkin

3 years ago

Works so well and helps keep my breakouts to none.

Sally Taylor

3 years ago

Dont be afraid of the strength its wonderful Love . I tried all % i love them all

Palmer Kuder

3 years ago

This product has really improved the texture of my skin.

Jessica Winters

3 years ago

This product works great alone or with the blender from the NuDerm system. This has helped with my fines lines and will not go without it !

Mariah Vasquez

3 years ago

feels great!

Alicia Donovan

3 years ago

The fountain of youth in a tube!

Linds Perugini

3 years ago

Works on fine lines

Zarah Celino

3 years ago

Amazing product

Tia Wells

3 years ago

A literal miracle in a tube. I was not good to my skin in my younger years. I am now fighting to turn back time and with this in my corner I have managed to do so.

Julie Krajicek

3 years ago

Great

JC Scanlon

3 years ago

Easy to apply with dotting method. My skin has racted well to it. I apply moisturizing cream 20-30 minutes after rubbing tretinoin in.

Lori Chance-Snell

3 years ago

One of my favorite products!!

Polina Farias

3 years ago

Excellent product’

Thanh Trang Thai

3 years ago

Great product!

Lara Colley

4 years ago

Use everyday for youthful skin. Mix it with Blender to get the most out of it.

Lisa Lamica

4 years ago

Seeing improvements quickly!

RayAnna Rogers

4 years ago

Love

Reyna. Medina

4 years ago

It’s the best product

Deja Eisenhour

4 years ago

I’ve used this for years. It’s a necessary product to keep that youthful look.

RavenTommy Breaux

4 years ago

Since using this product I have seen improvement in my skin! My acne has improved and I now have an overall glow. I will be purchasing again!

Jen Lee

4 years ago

The Best Tret on the Market!!

Katie Hayes

4 years ago

I have not had a peeling which my aesthetician is shocked! I’ve been on for 6 weeks and have noticed a difference

Liberty Davidson

4 years ago

Great results when used with the Blender product

Rebecca Truhe

4 years ago

This is the one product I am sure to never to go without! Love it in conjunction with Blender!

ALex Curiel

4 years ago

awesomeness

Need to Know

IMPORTANT SAFETY INFORMATION

Tretinoin Cream Indication: Tretinoin Cream is indicated for topical application in the treatment of acne vulgaris.

Important Safety Information: For Topical Use Only

Contraindications: Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

Please click here for full Prescribing Information.

IMPORTANT SAFETY INFORMATION

Tretinoin Cream Indication: Tretinoin Cream is indicated for topical application in the treatment of acne vulgaris.

Important Safety Information: For Topical Use Only

Contraindications: Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

Please click here for full Prescribing Information.

Precautions: Exposure to sunlight, including sunlamps, should be minimized during the use of Tretinoin Cream and Gel, and patients with sunburn should be advised not to use the product until fully recovered.

Patients who have considerable sun exposure due to occupation and those with inherent sensitivity to the sun should exercise particular caution. Use of sunscreen products and protective clothing over treated areas is recommended when exposure cannot be avoided.

Weather extremes, such as wind or cold, also may be irritating to patients using tretinoin.

Tretinoin Cream should be kept away from the eyes, the mouth, angles of the nose, and mucous membranes. Topical use may induce severe local erythema and peeling at the site of application. If the degree of local irritation warrants, patients should be directed to use the medication less frequently, discontinue use temporarily, or discontinue use altogether.

Tretinoin has been reported to cause severe irritation on eczematous skin and should be used with utmost caution in patients with this condition.

Pregnancy: Tretinoin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Adverse Reactions: The skin of certain sensitive individuals may become excessively red, edematous, blistered, or crusted. If these effects occur, treatment should be discontinued or adjusted to a level the patient can tolerate.

To report SUSPECTED ADVERSE REACTIONS contact FDA at fda.gov/medwatch or call 1-800-FDA-1088.

IMPORTANT SAFETY INFORMATION

Tretinoin Cream Indication: Tretinoin Cream is indicated for topical application in the treatment of acne vulgaris.

Important Safety Information: For Topical Use Only

Contraindications: Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

Please click here for full Prescribing Information.

How to Use

Morning Routine:

  • Apply a moisturizer, preferably with sunscreen, that will not aggravate your acne.

Nighttime Routine:

  • Wash with a mild soap and dry skin gently
  • Wait 20 to 30 minutes to allow skin to completely dry
  • Squeeze no more than half an inch of medication onto fingertip; more medication will not yield faster or better results and may cause irritation
  • Apply onto face, covering affected area lightly, starting with your forehead, chin, and both cheeks, then spread over the entire affected area
  • Avoid corners of the nose, mouth, eyes, and open wounds
  • Tretinoin is for topical use, only
  • Tretinoin should be applied once daily, or as directed by physician. Please ensure to always read and follow the Patient Instruction in the Prescribing Information leaflet that accompanies your tretinoin prescription
  • Tretinoin acne treatment should be kept away from the eyes, the mouth, paranasal creases, and mucous membranes
  • Application of excessive amounts of gel will not provide incremental efficacy
  • Store tretinoin cream at controlled room temperature below 80°F

Morning Routine:

  • Apply a moisturizer, preferably with sunscreen, that will not aggravate your acne.

Nighttime Routine:

  • Wash with a mild soap and dry skin gently
  • Wait 20 to 30 minutes to allow skin to completely dry
  • Squeeze no more than half an inch of medication onto fingertip; more medication will not yield faster or better results and may cause irritation
  • Apply onto face, covering affected area lightly, starting with your forehead, chin, and both cheeks, then spread over the entire affected area
  • Avoid corners of the nose, mouth, eyes, and open wounds
  • Tretinoin is for topical use, only
  • Tretinoin should be applied once daily, or as directed by physician. Please ensure to always read and follow the Patient Instruction in the Prescribing Information leaflet that accompanies your tretinoin prescription
  • Tretinoin acne treatment should be kept away from the eyes, the mouth, paranasal creases, and mucous membranes
  • Application of excessive amounts of gel will not provide incremental efficacy
  • Store tretinoin cream at controlled room temperature below 80°F

FAQs